can you give me a scientific basis that endometrial cancer can occur at the age of 30?me and my co-researchers already had our case study defense but the panelists did not accept my rationale that endo CA commonly occurs at the age bracket 55-70 and only 2 to 5 percent occurs below 40. our patient was 30 years old when she had the ENDO CA... they said, why such slim percentage for below 40....can u help me?
Answer by zrepmd
Two reasons come to mind:
1) First, MOST cancers occur in that age range, because cancer is primarily (by the numbers) a disease of older people, due to length of time it takes for genetic damage to accumulate and result in cancer.
2) Second, menstruation provides a monthly "cleansing" effect of rapidly growing/dividing cells which are highly influenced by hormone levels; these cells being shed lowers the risk for a women until she goes through menopause, when it ceases. I cannot tell you whether the changing hormone milieu is a cause in this or not. Supporting evidence for this: tamoxifen, a well-studied hormonal agent for treatment of breast cancer, is associated with increase risk of uterine cancer, though this risk is primarily confined to postmenopausal women.
Orignal From: can you give me a scientific basis that endometrial cancer can occur at the age of 30?
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