What does the "Grade" refer to in Endometrial cancer?My mother was diagnosed with "Grade 3." From what I understand, this means there is a lower concentration of Cancer cells than a "Grade 1", however they are far more aggressive. Is this accurate? Also, how fast moving is this cancer typically?
We are of course in the care of several doctors, and have appointments scheduled. A hysterectomy is a given, and chemotherapy to be determined following the surgery.
Thank you sincerely.
Answer by ssmc221
grades are used to determine how much cancer there is and how far it has spread, I myself had uterine cancer, I was diagnosed 3 years ago and went through, the hysterectomy, chemo and radiation. unfortunately there are several different kinds of cancer cells so it is hard to say if this is a fast moving cancer, mine was clear-cell which is a very aggressive type. There is good news and bd news to the aggressiveness of the different types, aggressive types of cancer obviously move fast but they react better to radiation and certain chemo's. Obviously, a slower moving cancer has the benefit of not spreading very quickly from one area to the other. I would suggest that you (or someone else) go with your mom to her appointments to ask questions and to help her retain the info they are giving her, It was hard to comprehend what the doctors were telling me (at first) and I was glad to have a second pair of ears.
Spreedog is right I was thinking of staging...sorry
Answer by Spreedog
"ssmc" is so right about having that "second pair of ears" present when the doctors are explaining things.
But "ssmc" is thinking perhaps of "stage" rather than grade.
The grade is more related to the level of differentiation of the tumor cells.
When pathologists look at the cancer cells under a microscope, the less the cells look like normal uterine endometrial cells, the more undifferentiated they are, and the more aggressive that particular malignancy is likely to be.
This has nothing to do with "concentration of cancer cells."
I'll look up a good site for you to read on this.
For staging - http://www.cancer.org/docroot/cri/content/cri_2_4_4x_treatment_options_by_stage_11.asp
And from http://www.canceranswers.com/Uterine.Cancer.html
"Adenocarcinoma is the most common type of uterine cancer, it arises from the glands of the endometrium. About 80% of uterine cancers are adenocarcinomas, and they have varying aggressiveness. The pathologist assigns a "grade" to this cancer, which basically says how cancerous it looks under the microscope. While "Grade I" looks a lot like normal uterine tissue and can be very indolent, "Grade III" looks very cancerous and will probably be aggressive. "Grade II" is intermediate in looks and behavior. About 40% of adenocarcinomas are "Grade I," 20% are "Grade II," and 40% are "Grade III." There may be a mixture of grades or even cancer types in the tumor."
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