BIOCHEMISTRY HELP: Lab Test?A patient with recent weight loss was evaluated and her A/G was low. Other tests that were given include:
Serum electrophoresis: No M-peak
ALT (serum glutamate-pyruvate transaminase): Normal
AST (SGOT): Slightly increased
Bilirubin (conjugated): High
GGT: High
Blood urea nitrogen: Normal
Creatine: Normal
Creatine clearance: Normal
Based on the information presented above the patient has:
a. Multiple myeloma
b. Cirrhossis
c. Kidney Disease
d. none of the above (something else)
Answer by Paul
Conjugated bilirubin, gamma-glutamyl-transpeptidase (GGT) and serum albumin (the A of A/G) are principally made in the liver. Aspartate transaminase (AST) is made in many tissues including liver cells. So the elevated enzymes and bilirubin all point to liver damage as does a low production of albumin. So B. Cirrhosis is the likely answer.
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