When can one start seeing chemotherapy treatment work?Its been 2 cycles already and the lump in my dads leg grew in size, from an M&M shape, to a 2cmX3cm spherical shape growing deeper. Sometimes he cant feel it in the morning, then at night he feels it. Its more prominant when my dads blood sugar is high. I read that tumors feed off of blood sugar. Shouldnt the chemotherapy stop the growth already? His doc said it was just scar tissue. Isnt there a test to figure out if the chemos working?
Its diffuse large B-cell lymphoma in the thigh, and the doc said theres an indolent type of lymphoma in the bone. She didnt say what the second was.
Hes on R-CHOP right now, every 3 weeks.
Answer by signpostmaker
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Answer by notalonewithcancer
Normally after the 3rd round of chemo a new scan or MRI is given to monitor the development. If they see its not working then they will likely change the chemo mix.. if it is working, they continue on and check again after another 3 rounds.
Answer by mary m
If it is getting bigger after the chemo was started, then it is not scar tissue. It sounds worrisome to me.
If there are other treatment options available, it might be a good idea to push for some followup scans 'sooner' rather than 'later.'
A lot depends on what kind of malignancy this is, and what the treatment goal is. If you and your dad are wanting to see a cure and the MD thinks that 'control' is the best he can do, then you need to have a serious talk and get on the same page.
Good luck.
Answer by quijibored
The idea that cancer feeds off of sugar is based on a misconception of cancer biology and an incomplete understanding of how PET scans work.
When you have a PET scan done you quit eating any sugar or carbs prior to the test because most tumors consume more glucose than normal body organs. Tumors have an increased blood supply and this increased vascular supply helps feed the glucose into the tumor. Having no excess glucose in the bloodstream makes the tumors light up much better on PET scans.
All aspects of metabolism in the human body are dependent on glucose for fuel. You can not stop consuming enough glucose to make any difference in the growth of a tumor because the tumor always gets first dibs on any glucose that becomes available. In other words, you would starve to death before your reducing your glucose intake would have any affect on the growth of the tumor.
Your father could have a PET scan and this would tell if the tumor is still active or not. If your dad has medicare for his insurance you should know that medicare does not like to pay for PET scans but if they are medically necessary and he has his Dr's support it is possible to get a PET scan approved by and paid for by medicare.
all the best to you both
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