what is gram negative sepsis shock and why is my brother in law dying from it?He Has had multiple myeloma for 1 year and now his proteins in his blood spiked in 1 week, now has tumours on liver, bowell etc. On total life support till we decide what to do.
Answer by abijann
Gram Negative refers to a type of bacteria.
Our bodies have white blood cells. These white blood cells
are known as our immune system. When anything foreign
comes into the body, the white cells react and, like soldiers,
fight off the bacteria that enters. There are different kinds
of white blood cells: neutrophils, basophils, eosinophils,
lymphoctyes, monocytes and others. Each one has a job
to do as far as removing the bacteria from the body.
When the immune system responds to the bacteria, it
creates a wall, or inflammation, that will try to stop the
bacteria from going any further into the body.
Inflammation causes swelling.
Normally, this swelling (inflammation) would only be in
the area (or organ) where the problem is.
For example: the patient has damage to the liver cells,
the immune system responds to this and cause inflammation
to develop inside the liver, this will cause the liver to enlarge
in size. If the cause of the inflammation is not stopped, it
can lead to where the liver cells die off and form scar
tissue inside the liver which will block the flow of blood.
This gram negative bacteria is probably in his blood and is
causing inflammation in his entire body in different areas.
This is serious because it will eventually cause the blood not
to flow well. It leads to slowing of the blood flow and clots.
The Red Blood Cells of the body are what transports oxygen
throughout the body. The lack of oxygen to the organs can
make them go into failure.
http://www.merckmanuals.com/professional/sec06/ch068/ch068a.html
The doctors can start him on combinations of antibiotics to try
to fight off this bacteria, IV's, and anti-inflammatory medications.
This is the best I can do to explain this. However, I'm not a
medical professional and this should be taken as info and not
fact.
I believe I would talked to the doctor more about this and get
their professional opinion on his chances. They can give you
an educated "guess" from the tests they do...whether he
may pull through this.
I hope this has been of some help to you. Best wishes
Answer by Touscents
I am very sorry. Your brother in law should not be kept on life support. Gram negative sepsis is bacterial infection of the blood. Myeloma is a devestating cancer of white blood cells. They lose their ability to fight off infection, amoung other problems. The cancer has spread beyond control and together with the infection, will rapidly ravage and kill your brother in law, even if he is on life support. If the doctor confirms this, then It is not humane to keep him on life support.
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