What is the difference between B and T memory cells?I know they're produced in different places (Bone marrow and Thymus), but what is the actual difference?
B memory cells divide into plasma cells, producing antibodies, but what do T memory cells do? Do they just divide into T helper and T Surpressor? Please help?!
Answer by FrgRes11
Naive B cells are developed in the bone marrow. Once the are mature, they move into other areas of the body where they see antigen (something foreign). This activates the B cells to produce antibodies. Once they begin to produce antibodies, B cells go through class switching and somatic hypermutation to develop better antibodies that bind the antigen better. They then differentiate into long term plasma cells, which are the memory cells, that will make this "better" antibody upon interaction with antigen again and live in the bone marrow or spleen, primarily.
Naive T cells are formed in the thymus. They then leave the thymus and go to the lymph nodes, where they will see antigen. There are two main type of T cells that protect from antigen, helper T cells and cytolytic T cells. Helper T cell produce things to help cytolytic T cells and B cells do their jobs. Cytolytic (or cell-killing) cells can produce molecules that kill other cells, mostly cells that are infected with virus. After these cells become activated that expand to large numbers, then when the threat is killed, most of them will die. A few live long term and develop into memory T cells. These cells are long lived and will kill the antigen again when they see it. They primarily live in the thymus, and do not produce antibodies.
T supressor cells are something else entirely, and really don't have anything to do with memory.
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